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Ingredient science

The science behind the label.

Doctor-reviewed ingredient dossiers. Doses, sourcing, mechanism, and what the clinical evidence actually shows.

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Sulforaphane Rich Foods for Cellular Longevity
longevity
Sulforaphane Rich Foods for Cellular Longevity
N-Acetylcysteine for Mucus Clearance: Evidence and Usage
immune
N-Acetylcysteine for Mucus Clearance: Evidence and Usage
Macronutrient Ratios for Weight Loss: Evidence-Based Guidelines
weight
Macronutrient Ratios for Weight Loss: Evidence-Based Guidelines
Sulforaphane Rich Foods for Cellular Longevity
longevity · Editor's pick

Sulforaphane Rich Foods for Cellular Longevity

Sulforaphane rich foods can help promote cellular longevity by reducing inflammation and oxidative stress. Learn how to add these foods to your diet for a healthier life.

Ingredient of the week

Berberine HCL

Isoquinoline alkaloid · Studied at 500 mg 3×/day

Extracted from Berberis plants, this compound activates AMPK — the same cellular pathway metformin targets. Human trials at clinical doses show modest reductions in fasting glucose and HbA1c comparable to first-line pharmaceuticals, with GI side effects at higher intakes.

Clinical dose
1500 mg/day
Bioavailability
~5%
Trials reviewed
27
Evidence strength
SpeculativeEstablished
Blood sugar Lipid profile Gut microbiome
Recent dossiers

Latest dossiers

N-Acetylcysteine for Mucus Clearance: Evidence and Usage
immune · By Dr. David Park, MD

N-Acetylcysteine for Mucus Clearance: Evidence and Usage

Learn how N-Acetylcysteine functions as a mucolytic agent to thin respiratory secretions. This evidence-based overview covers mechanisms, dosage…

4 min read · July 9, 2026
Macronutrient Ratios for Weight Loss: Evidence-Based Guidelines
weight · By Dr. David Park, MD

Macronutrient Ratios for Weight Loss: Evidence-Based Guidelines

Finding the right balance of protein, carbs, and fat influences satiety and metabolism. Evidence shows moderate-protein, lower-carb ratios…

3 min read · July 9, 2026
Adaptogenic Mushrooms for Enhanced Endurance: Evidence and Practical Use
energy · By Dr. Aisha Okonkwo, PhD

Adaptogenic Mushrooms for Enhanced Endurance: Evidence and Practical Use

Adaptogenic mushrooms such as cordyceps and reishi are studied for their potential to improve aerobic capacity and fatigue…

4 min read · July 9, 2026
Vagus Nerve Stimulation for Mood Regulation: Evidence-Based Approaches
mood · By Dr. Hannah Björklund, ND

Vagus Nerve Stimulation for Mood Regulation: Evidence-Based Approaches

The vagus nerve connects brain and body, playing a key role in mood regulation through parasympathetic signaling. This…

5 min read · July 9, 2026
Blue Light Filtering for Digital Eye Strain Relief: Evidence
vision · By Dr. James Whitfield, ND

Blue Light Filtering for Digital Eye Strain Relief: Evidence

Extended screen time can cause digital eye strain, but blue light filtering offers a measurable way to ease…

5 min read · July 9, 2026
Optimizing Your Lipid Profile Through Diet: Evidence-Based Strategies
nutrition · By Dr. Marco Lanza, MD

Optimizing Your Lipid Profile Through Diet: Evidence-Based Strategies

Discover which foods and nutrients help lower LDL cholesterol and triglycerides while raising HDL. Practical, evidence‑based steps guide…

5 min read · July 9, 2026
Extended library

Ingredient library

55-70 chars
detox · By Dr. Aisha Okonkwo, PhD

55-70 chars

2-sentence excerpt 160-200 chars

1 min read · July 9, 2026
Licorice Root for Gut Soothing: Evidence-Based Benefits and Use
gut · By Dr. Ravi Patel, MD, MPH

Licorice Root for Gut Soothing: Evidence-Based Benefits and Use

Licorice root has been studied for its potential to calm irritated gut lining and reduce inflammation. Learn the…

4 min read · July 9, 2026
Boost Focus with Pomodoro Technique
focus · By Dr. Elena Vargas, PhD, RD

Boost Focus with Pomodoro Technique

The Pomodoro Technique is a simple yet effective method to boost concentration and productivity. By working in focused…

3 min read · July 9, 2026
55-70 chars - precise, intriguing, NOT clickbait
heart · By Dr. David Park, MD

55-70 chars - precise, intriguing, NOT clickbait

2-sentence excerpt 160-200 chars

1 min read · July 9, 2026
Thyroid Supporting Foods for Hormone Balance: Evidence-Based Choices
hormones · By Dr. Marco Lanza, MD

Thyroid Supporting Foods for Hormone Balance: Evidence-Based Choices

Your thyroid relies on key nutrients like iodine and selenium to produce hormones that regulate metabolism, mood, and…

4 min read · July 9, 2026
Finding the Ideal Bedroom Temperature for Better Sleep at Home
sleep · By Dr. James Whitfield, ND

Finding the Ideal Bedroom Temperature for Better Sleep at Home

Room temperature influences melatonin release and core body cooling, key factors for sleep onset. Adjusting your bedroom to…

4 min read · July 9, 2026
Clinical panel

Reviewed by physicians

AO
Dr. Aisha Okonkwo, PhD
PhD in Clinical Nutrition (Cornell). Author of three peer-reviewed papers on micronutrient therapy.
DP
Dr. David Park, MD
Sleep medicine specialist (Stanford Sleep Center). Researches circadian biology and recovery.
EV
Dr. Elena Vargas, PhD, RD
Registered Dietitian and PhD in Exercise Physiology. Researches sports nutrition and energy metabolism.
HB
Dr. Hannah Björklund, ND
Naturopath specializing in hormonal balance and women's wellness. Stockholm-trained.
Certifications decoded

Certifications, decoded

Certifications on a label look uniform but mean different things. Here is what each mark actually verifies.

FDA-Registered Facility
The manufacturing site is registered with the FDA, meaning it is inspected for basic sanitation and record-keeping. It does NOT mean the supplement itself is FDA-approved (supplements never are).
GMP-Certified
Good Manufacturing Practice — an independent audit verifies the facility follows consistent quality control, batch testing, and contamination prevention. A meaningful indicator of production reliability.
Non-GMO
Ingredients are not derived from genetically modified organisms. Not the same as "organic" — non-GMO says nothing about pesticide use or farming practices.
3rd-Party Tested
An independent lab (NSF, USP, ConsumerLab, or similar) verified ingredient identity, dosage accuracy, and absence of contaminants. The strongest quality signal.
Made in USA
Final product manufactured on US soil under US labor and safety regulations. Raw ingredients may still come from international suppliers.
180-day Money-Back
Full refund window from purchase date. Longer guarantees indicate manufacturer confidence in results and lower financial risk for the first-time buyer.
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30 articles
Focus
21 articles
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20 articles
Gut
19 articles
Heart
23 articles
Joints
14 articles
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18 articles
Hormones
30 articles
Mood
19 articles
Weight
18 articles
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13 articles
Longevity
26 articles
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25 articles
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The supphealth dispatch

A weekly ingredient dossier. New dose data, mechanism updates, ingredient watchlists.